Gene defect may be a cause of asthenozoospermia

This study characterised the gene Cfap97 domain containing 1 (Cfap97d1) for its role in sperm tail formation. They found that Deletion of the Cfap97d1 gene in both mouse models leads to sperm motility defects (asthenozoospermia) and male subfertility. IVF of normal eggs failed.

https://pubmed.ncbi.nlm.nih.gov/32785227/

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